All mammals are susceptible to rabies infection. The rabies vaccine is safe and effective for a variety of domestic animals, including dogs, cats, sheep, cattle, horses, and ferrets. Using vaccines for wildlife and hybrid animals (wildlife crossbred with domestic dogs or cats) is not licensed and is strongly discouraged.
Unvaccinated dogs or cats exposed to a rabid animal (including untested bats) should be euthanized and examined. If the owner refuses to sacrifice their pet, the animal should be quarantined for a 6-month period, with rabies vaccination administered in the final month of quarantine.